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Nitric oxide and infants


Keywords:
Description:
The journal article describes an experiment to see if inhaled nitric oxide helps infants with respiratory distress syndrome.
Information:
Of interest here is the method uses and the reporting. The Methods section begins
We conducted a randomized, double-blind, placebo-controlled study of the effect of inhaled nitric oxide during the first week of life on the incidence of chronic lung disease and death in premature infants (less than 34 weeks' gestation)...
The Results section states
A total of 207 premature infants were enrolled. In th egroup given nitric oxide, 51 infants (48.6 percent) died or had chronic lung disease, as compared with 65 infants (63.7 percent) in the placebo group (relative risk, 0.76; 95 percent confidence interval, 0.60 to 0.97; P=0.03).
Source:
Schreiber, Michael D, et al. Inhaled nitric oxide inpremature infants with the respiratory distress syndrome. New England Journal of Medicine, 349, November 27, 2003.
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