Datasets for Statistical Analysis

Cell mutant frequencies in children

Keywords:

cells; mutation; hprt locus

Categories:

generalized linear models;
science

Description:

The data give the "somatic cell mutant frequencies at the hrpt locus of the X-chormosome" in healthy children.

There are 49 observations on four variables, plus an identifier

Variables:

Donor	The donor identifier
Sex	The sex of the child; either M for males or F for females
Age	The age of the child (in years)
Ceff	The mean unselected cloning efficiency
Mfreq	The mutant frequencies (×10-6)

Data Quality:

There are no missing values.

Source:

Finette, Sullivan, O'Neill, Nicklas, Vacek and Albertini (1994). Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age, in Mutation Research, 308, 223--231.

Notes:

In the original paper, the children are sometimes referred to as belongiong to Group II (Ages 0 to 5), Group III (Ages 6 to 11) or Group IV (Ages 12 to 17). (Group I refers to cord data referenced to another article.) The Ages may be treated as categorical with these categories.

References: